The UK NSC recommendation on Neuroblastoma screening in infants
Find general information about population health screening.
Why is screening not recommended by UK NSC?
- there is no evidence of a screening test that would only detect people with Neuroblastoma needing treatment
- some low quality studies suggest screening at a later age may ensure only children who would benefit from treatment are detected. However no high quality studies have assessed the effect of screening at 18 months. This is either compared to no screening, or to screening at six or 12 months
- no studies addressed the main concern that screening could lead to treating more people who would not have needed treatment
- ultimately, there is no evidence that screening would reduce deaths from neuroblastoma
More about Neuroblastoma
Neuroblastoma is a malignant childhood cancer and leukaemia of the sympathetic nervous system. Most tumours arise from the centre (medulla) of the adrenal gland which lies above the kidney. Other sites of the disease include the chest, the spine and the pelvis. Some tumours may disappear without treatment.
» Read more about neuroblastoma on NHS Choices
• The British Association for Cancer Research
• British Association of Surgical Oncology
• Cancer Research UK
• CLIC Sargent
• The Henry Allen Trust
• Institute of Child Health
• The Neuroblastoma Society
• Rarer Cancers Forum
• Royal College of Paediatrics and Child Health
• Royal College of Physicians
• Royal College of Physicians of Edinburgh
• Royal College of Surgeons
The stakeholder groups will be involved when the recommendation is next reviewed.
If you think your organisation should be added, please
More information for stakeholders can be found in appendix C of the UK NSC evidence review process.
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